10 Facts About Aciclovir

1.

Aciclovir was patented in 1974, and approved for medical use in 1981.

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2.

Aciclovir is used for the treatment of herpes simplex virus and varicella zoster virus infections, including:.

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3.

Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles.

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4.

Aciclovir trials show that this agent has no role in preventing HIV transmission, but it can help slow HIV disease progression in people not taking anti-retroviral therapy.

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5.

Aciclovir is recommended by the CDC for treatment of varicella during pregnancy, especially during the second and third trimesters.

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6.

Aciclovir is excreted in the breast milk, therefore it is recommended that caution should be used in breast-feeding women.

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7.

Aciclovir is active against most species in the herpesvirus family.

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8.

Aciclovir is poorly water-soluble and has poor oral bioavailability, hence intravenous administration is necessary if high concentrations are required.

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9.

Aciclovir was seen as the start of a new era in antiviral therapy, as it is extremely selective and low in cytotoxicity.

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10.

Aciclovir is the international nonproprietary name and British Approved Name while acyclovir is the United States Adopted Name and former British Approved Name.

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