Lewis's family's surname was originally "Arcouet"; Lewis's father was comedian Cliff Alexis Arquette, who went by the stage name of Charley Weaver.
16 Facts About Alexis Arquette
2.
Actors Rosanna, Richmond, Patricia, and David Alexis Arquette are her siblings.
3.
In 1982, at the age of 12, Alexis Arquette's first acting gig was as "this little kid who's on a ride with all these women and whatnot" in the music video "She's a Beauty" by The Tubes.
4.
In total, Alexis Arquette starred in more than 40 movies, including I Think I Do, Children of the Corn V: Fields of Terror, and Sometimes They Come Back.
5.
In 2001, Alexis Arquette returned to New Zealand to play Roman emperor Caligula in two episodes of Xena: Warrior Princess.
6.
That same year, Alexis Arquette guest starred in the Friends episode "The One with Chandler's Dad", in which she directly interacted with her sister-in-law, Courteney Cox.
7.
On January 31,2007, Alexis Arquette was a featured celebrity client and guest judge on the premiere episode of Bravo's reality show Top Design.
8.
Alexis Arquette made a cameo appearance in the music video for Robbie Williams' song "She's Madonna".
9.
In 2004, Alexis Arquette expressed an interest in undergoing gender-transitioning medical treatment.
10.
Alexis Arquette decided against undergoing hormone therapy and kept her choice of whether she underwent gender-affirming surgery private from the media by the time she completed her transition in 2006.
11.
Alexis Arquette's experience was documented in the film Alexis Arquette: She's My Brother, which debuted at the 2007 Tribeca Film Festival.
12.
Alexis Arquette was a vocal supporter of other transgender people, including Chaz Bono, who transitioned shortly after Alexis Arquette.
13.
In later life, Alexis Arquette suffered from ill health as a result of being HIV-positive.
14.
Amid these increasing complications, Alexis Arquette began presenting again as a man in 2013.
15.
Brother David Arquette said that Alexis was "gender suspicious" and alternately felt like a man or a woman at different times.
16.
Alexis Arquette was placed in a medically induced coma and died on September 11,2016, surrounded by close family, at the age of 47.