Anastrozole, sold under the brand name Arimidex among others, is a medication used in addition to other treatments for breast cancer.
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10 Facts About Anastrozole
2.
Anastrozole was patented in 1987 and was approved for medical use in 1995.
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3.
Anastrozole is used in the treatment and prevention of breast cancer in women.
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4.
Anastrozole is thought to have clinically negligible inhibitory effects on the cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2D6, CYP2C8, CYP2C9, and CYP2C19.
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5.
Anastrozole is excreted primarily in urine but to a lesser extent in feces.
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6.
Anastrozole is structurally related to letrozole, fadrozole, and vorozole, with all being classified as azoles.
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7.
Anastrozole was patented by Imperial Chemical Industries in 1987 and was approved for medical use, specifically the treatment of breast cancer, in 1995.
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8.
Anastrozole is the generic name of the drug and its INN, USAN, BAN, and JAN.
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9.
Anastrozole is surprisingly ineffective at treating gynecomastia, in contrast to selective estrogen receptor modulators like tamoxifen.
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10.
Anastrozole was under development for the treatment of female infertility but did not complete development and hence was never approved for this indication.
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