10 Facts About Anastrozole

1.

Anastrozole, sold under the brand name Arimidex among others, is a medication used in addition to other treatments for breast cancer.

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2.

Anastrozole was patented in 1987 and was approved for medical use in 1995.

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3.

Anastrozole is used in the treatment and prevention of breast cancer in women.

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4.

Anastrozole is thought to have clinically negligible inhibitory effects on the cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2D6, CYP2C8, CYP2C9, and CYP2C19.

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5.

Anastrozole is excreted primarily in urine but to a lesser extent in feces.

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6.

Anastrozole is structurally related to letrozole, fadrozole, and vorozole, with all being classified as azoles.

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7.

Anastrozole was patented by Imperial Chemical Industries in 1987 and was approved for medical use, specifically the treatment of breast cancer, in 1995.

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8.

Anastrozole is the generic name of the drug and its INN, USAN, BAN, and JAN.

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9.

Anastrozole is surprisingly ineffective at treating gynecomastia, in contrast to selective estrogen receptor modulators like tamoxifen.

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10.

Anastrozole was under development for the treatment of female infertility but did not complete development and hence was never approved for this indication.

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