10 Facts About Anastrozole


Anastrozole, sold under the brand name Arimidex among others, is a medication used in addition to other treatments for breast cancer.

FactSnippet No. 1,457,489

Anastrozole was patented in 1987 and was approved for medical use in 1995.

FactSnippet No. 1,457,490

Anastrozole is used in the treatment and prevention of breast cancer in women.

FactSnippet No. 1,457,491

Anastrozole is thought to have clinically negligible inhibitory effects on the cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2D6, CYP2C8, CYP2C9, and CYP2C19.

FactSnippet No. 1,457,492

Anastrozole is excreted primarily in urine but to a lesser extent in feces.

FactSnippet No. 1,457,493

Anastrozole is structurally related to letrozole, fadrozole, and vorozole, with all being classified as azoles.

FactSnippet No. 1,457,494

Anastrozole was patented by Imperial Chemical Industries in 1987 and was approved for medical use, specifically the treatment of breast cancer, in 1995.

FactSnippet No. 1,457,495

Anastrozole is the generic name of the drug and its INN, USAN, BAN, and JAN.

FactSnippet No. 1,457,496

Anastrozole is surprisingly ineffective at treating gynecomastia, in contrast to selective estrogen receptor modulators like tamoxifen.

FactSnippet No. 1,457,497

Anastrozole was under development for the treatment of female infertility but did not complete development and hence was never approved for this indication.

FactSnippet No. 1,457,498