16 Facts About Angelo Maffucci


Angelo Maria Maffucci was an Italian pathologist of the nineteenth century.


Angelo Maria Maffucci was an Italian pathologist born in the town of Calitri in the province of Avellino on October 27,1847, from a family of farmers, son of Michele and Benedetta Nicolais.


Angelo Maffucci was a member of numerous academies and scientific societies, including the Accademia Nazionale dei Lincei, and he received from the Venetian Institute of Sciences, Letters and Arts a prize for the progress in Medical Sciences.


Angelo Maffucci retired to Vallombrosa, near Florence, from were he wrote to the Minister of Education:.


The desired improvement did not occur and Angelo Maffucci died in Pisa on November 24,1903 at the age of 56.


Angelo Maffucci had described in 1881 the diseases for the first time, in a 40-year-old woman, hospitalized for a vascular tumor prone to severe and frequent bleeding, which died from complications resulting from amputation of the limb.


Angelo Maffucci's Syndrome is generally caused by mutations in the IDH1 or IDH2 gene.


Angelo Maffucci's Syndrome is not inherited as the mutations which cause it are somatic.


Angelo Maffucci was the first to isolate the pathogen of avian tuberculosis and described its peculiarities compared to the pathogens of the human and bovine variant.


Angelo Maffucci always carried with him a small album in which he illustrated the histological profiles of the pathologies of the system nervous, especially of cauda equina, and the effects of congenital syphilis in the liver, lungs and bones.


Angelo Maffucci continued his anatomical and experimental studies on liver pathology, making the important pathogenetic distinction between atrophic cirrhosis resulting from stagnation of bile by occlusion of the bile ducts, and hypertrophic cirrhosis ichthyic result of chronic inflammation of the biliary tract.


Angelo Maffucci described unusual anatomical pathological pictures and conducted experimental observations on the pathophysiology of the peritoneum, describing the mechanism of resorption of corpuscular substances capable of determining structural modifications.


Angelo Maffucci worked on the full development on the infectious etiology of neoplasms, he conducted numerous observations aimed at identifying a possible pathogen responsible for tumor growth: the isolation in some cases of streptococci and blastomycetes did not seem significant enough to attribute to these microorganisms a certain etiopathogenetic role in the appearance of tumors.


Angelo Maffucci had a revolutionary role in the position of Pisa in the field of Pathological Anatomy, since he founded the institute and the museum, both annexed to the medical school.


Angelo Maffucci divided the teaching into theoretical and practical, and his contribution was so important that it is possible to state that Pisa, thanks to Angelo Maffucci, was the first Italian university in which students had the opportunity, in the course of their studies, to associate the practical activity with the theoretical teaching.


Angelo Maffucci showed the same commitment in setting up and then enriching the Museum of Pathological Anatomy: to the important collection of collected preparations by Filippo Civinini in 1839, Maffucci added many other finds of various kinds, concerning, in particular, bone pathologies.