11 Facts About Aplastic anemia


Aplastic anemia is a disease in which the body fails to produce blood cells in sufficient numbers.

FactSnippet No. 2,055,492

Aplastic anemia can be definitively diagnosed by bone marrow biopsy.

FactSnippet No. 2,055,493

Aplastic anemia is known to have caused the deaths of Eleanor Roosevelt and Marie Curie.

FactSnippet No. 2,055,494

Aplastic anemia can be caused by immune disease or exposure to certain chemicals, drugs, radiation, or infection; in about half the cases, a definitive cause is unknown.

FactSnippet No. 2,055,495

Aplastic anemia is sometimes associated with exposure to toxins such as benzene or with the use of certain drugs, including chloramphenicol, carbamazepine, felbamate, phenytoin, quinine, and phenylbutazone.

FactSnippet No. 2,055,496

Marie Curie, famous for her pioneering work in the field of radioactivity, died of aplastic anemia after working unprotected with radioactive materials for a long period of time; the damaging effects of ionizing radiation were not then known.

FactSnippet No. 2,055,497

Aplastic anemia is associated with increased levels of Th17 cells—which produce pro-inflammatory cytokine IL-17—and interferon-?-producing cells in the peripheral blood and bone marrow.

FactSnippet No. 2,055,498

Study of blood and bone marrow samples obtained from 18 aplastic anemia patients revealed more than 30 potential specific candidate autoantigens after the serologic screening of a fetal liver library with sera from 8 patients.

FactSnippet No. 2,055,499

Aplastic anemia is a combination of two ancient Greek elements: a- and -plasis.

FactSnippet No. 2,055,500

Aplastic anemia is a rare, noncancerous disorder in which the blood marrow is unable to adequately produce blood cells required for survival.

FactSnippet No. 2,055,501

Those with a higher risk for aplastic anemia include individuals who are exposed to high-dose radiation or toxic chemicals, take certain prescription drugs, have pre-existing autoimmune disorders or blood diseases, or are pregnant.

FactSnippet No. 2,055,502