Aplastic anemia is a disease in which the body fails to produce blood cells in sufficient numbers.
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11 Facts About Aplastic anemia
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2.
Aplastic anemia can be definitively diagnosed by bone marrow biopsy.
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3.
Aplastic anemia is known to have caused the deaths of Eleanor Roosevelt and Marie Curie.
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4.
Aplastic anemia can be caused by immune disease or exposure to certain chemicals, drugs, radiation, or infection; in about half the cases, a definitive cause is unknown.
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Aplastic anemia is sometimes associated with exposure to toxins such as benzene or with the use of certain drugs, including chloramphenicol, carbamazepine, felbamate, phenytoin, quinine, and phenylbutazone.
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6.
Marie Curie, famous for her pioneering work in the field of radioactivity, died of aplastic anemia after working unprotected with radioactive materials for a long period of time; the damaging effects of ionizing radiation were not then known.
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7.
Aplastic anemia is associated with increased levels of Th17 cells—which produce pro-inflammatory cytokine IL-17—and interferon-?-producing cells in the peripheral blood and bone marrow.
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8.
Study of blood and bone marrow samples obtained from 18 aplastic anemia patients revealed more than 30 potential specific candidate autoantigens after the serologic screening of a fetal liver library with sera from 8 patients.
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9.
Aplastic anemia is a combination of two ancient Greek elements: a- and -plasis.
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10.
Aplastic anemia is a rare, noncancerous disorder in which the blood marrow is unable to adequately produce blood cells required for survival.
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11.
Those with a higher risk for aplastic anemia include individuals who are exposed to high-dose radiation or toxic chemicals, take certain prescription drugs, have pre-existing autoimmune disorders or blood diseases, or are pregnant.
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