Bone marrow is a semi-solid tissue found within the spongy portions of bones.
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Bone marrow is a semi-solid tissue found within the spongy portions of bones.
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Human Bone marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary cavity.
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Composition of Bone marrow is dynamic, as the mixture of cellular and non-cellular components shifts with age and in response to systemic factors.
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In humans, Bone marrow is colloquially characterized as "red" or "yellow" Bone marrow depending on the prevalence of hematopoietic cells vs fat cells.
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At the cellular level, the main functional component of bone marrow includes the progenitor cells which are destined to mature into blood and lymphoid cells.
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Human Bone marrow produces approximately 500 billion blood cells per day.
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Stroma of the bone marrow includes all tissue not directly involved in the marrow's primary function of hematopoiesis.
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Bone marrow stroma contains mesenchymal stem cells, which are known as marrow stromal cells.
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Blood vessels of the bone marrow constitute a barrier, inhibiting immature blood cells from leaving the marrow.
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Red bone marrow is a key element of the lymphatic system, being one of the primary lymphoid organs that generate lymphocytes from immature hematopoietic progenitor cells.
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Animal bone marrow has been used in cuisine worldwide for millennia, such as the famed Milanese Ossobuco.
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The bone marrow can be affected by various forms of leukemia, which attacks its hematologic progenitor cells.
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Bone marrow derived stem cells have a wide array of application in regenerative medicine.
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Furthermore, normal fatty Bone marrow loses signal on fat-saturation sequences, in a similar pattern to subcutaneous fat.
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When "yellow" fatty Bone marrow becomes replaced by tissue with more cellular composition, this change is apparent as decreased brightness on T1-weighted sequences.
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Normal "red" Bone marrow is typically equivalent or brighter than skeletal muscle or intervertebral disc on T1-weighted sequences.
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Bone marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, anemia, and pancytopenia.
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The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells.
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The patient's own Bone marrow is first killed off with drugs or radiation, and then the new stem cells are introduced.
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