10 Facts About Dale Sanders

1.

Dale Sanders, FRS was born on 13 May 1953 and was Director of the John Innes Centre, an institute for research in plant sciences and microbiology in Norwich, England.

2.

Dale Sanders gained a Bachelor of Arts degree from the University of York reading Biology from 1971 to 1974, graduating with 1st Class Honours.

3.

The Dale Sanders lab demonstrated a key link between changes in cytosolic free calcium and photosynthetic activity, and through many technical developments showed how membrane transport at the plant vacuole is energised and regulated in response to physiological demand.

4.

Dale Sanders adapted electrophysiological techniques first developed for exploration of neuronal channel properties to determine that pumps at vacuolar membranes exhibit kinetic responses to ion gradients that would not be predicted through biochemical means.

5.

Dale Sanders discovered and characterised the first yeast calcium channel and demonstrated how cell marking can be used to distinguish cell types for patch clamp studies.

6.

Dale Sanders had influence in the investigation into the roles of plant cyclic nucleotide-gated channels that were explored at an early stage of discovery and resulted in a major collaborative publication with another lab demonstrating a key role in plant-bacterial symbiosis signalling.

7.

Dale Sanders then established the principal molecular and cellular mechanisms for plant tolerance to manganese toxicity.

8.

Dale Sanders has discovered the major mechanism of zinc accumulation in plant vacuoles, and more recently characterised the molecular properties of the transporter and showed how the transporter could be used for nutritional benefit for human consumption of cereal grains.

9.

In 2010 Dale Sanders moved to the John Innes Centre, Norwich, as director and group leader, establishing new collaborations with the Chinese Academy of Sciences.

10.

Dale Sanders was elected a Fellow of the Royal Society in 2001.