14 Facts About Denis Noble

Denis Noble is one of the pioneers of systems biology and developed the first viable model of the working heart in 1960.

Denis Noble's research focuses on using computer models of biological organs and organ systems to interpret function from the molecular level to the whole organism.

Denis Noble is a philosopher of biology, with many publications in journals and books of philosophy.

Denis Noble explains that genes in fact work in groups and systems, so that the genome is more like a set of organ pipes than a "blueprint for life".

Denis Noble then suggests that there is no empirical difference between these statements, and says that they differ in "metaphor" and "sociological or polemical viewpoint".

Denis Noble has called for an extended evolutionary synthesis, and a replacement for the modern synthesis known as The Third Way of Evolution.

Denis Noble has argued that from research in epigenetics, acquired characteristics can be inherited and in contrast to the modern synthesis, genetic change is "far from random" and not always gradual.

Denis Noble has claimed that the central dogma of molecular biology has been broken as an "embodiment of the Weismann Barrier", and a new synthesis will integrate research from physiology with evolutionary biology.

Denis Noble's major invited lectures include the Darwin Lecture for the British Association in 1966, the Nahum Lecture at Yale in 1977 and the Ueda lecture at Tokyo University in 1985 and 1990.

Denis Noble was elected an Honorary Member of the Royal College of Physicians in 1988 and an Honorary Fellow in 1994, an Honorary Member of the American Physiological Society in 1996 and of the Physiological Society of Japan in 1998.

Denis Noble has honorary doctorates from the University of Sheffield, the Universite de Bordeaux and the University of Warwick.

Denis Noble is an Honorary Foreign Member of the Academie Royale de Medecine de Belgique, of the Istituto Lombardo Accademia di Scienze e Lettere, and received the Pavlov Medal of the Russian Academy of Sciences.

Denis Noble was born in London in 1936 to working-class tailors, George and Ethel Denis Noble.

Denis Noble plays classical guitar and sings Occitan troubadour and folk songs.