1. Edwin Southern is most widely known for the invention of the Southern blot, published in 1975 and now a common laboratory procedure.
14 Facts About Edwin Southern
1. 2.
Edwin Southern has a brother named John Southern and a sister Kay Monie.
3.
Edwin Southern continued as a graduate student in the Department of Chemistry, University of Glasgow, where he was awarded his PhD in 1962.
4.
Edwin Southern is the founder and chairman of Oxford Gene Technology.
5.
Edwin Southern is the founder and chairman of a Scottish charity, The Kirkhouse Trust, which aims to promote education and research in the Natural Sciences, particularly the biological and medical sciences, and the Edina Trust, which was founded to promote science in schools.
6.
The Edwin Southern blot is used for DNA analysis and was routinely used for genetic fingerprinting and paternity testing prior to the development of microsatellite markers for this purpose.
7.
The concepts of the Edwin Southern blot were used in the development and creation of the modern microarray slide, which is an extensively used experimental tool.
8.
Edwin Southern founded Oxford Gene Technology in 1995, a company that developed DNA microarray technology.
9.
In 1990, Edwin Southern was one of the winners of the Gairdner Foundation International Award.
10.
Edwin Southern received the Association for Molecular Pathology Award for Excellence in Molecular Diagnostics in 1999.
11.
Edwin Southern was made a Knight Bachelor in the June 2003 Birthday Honours for services to the development of DNA microarray technologies.
12.
Dr Edwin Southern has done pioneering work on the organization of DNA sequences in chromosomes.
13.
Apart from studies on crab poly-AT carried out in the early 1960s, Edwin Southern was the first to determine the nucleotide sequence of a eukaryotic chromosomal DNA fraction, demonstrating that a guinea pig 'satellite' had an unexpectedly simple repetitive structure based on a sequence of six nucleotides.
14.
Edwin Southern has made important observations on the differential transcription of DNA sequences into RNA, and on patterns of DNA methylation.