14 Facts About Escitalopram

Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor class.

Escitalopram is mainly used to treat major depressive disorder and generalized anxiety disorder.

Escitalopram is the -enantiomer of citalopram, hence the name es-citalopram.

Escitalopram was approved for medical use in the United States in 2002.

Escitalopram is rarely replaced by twice the dose of citalopram, though escitalopram is safer and more effective.

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Escitalopram has FDA approval for the treatment of major depressive disorder in adolescents and adults, and generalized anxiety disorder in adults.

Escitalopram was approved by regulatory authorities for the treatment of major depressive disorder on the basis of four placebo-controlled, double-blind trials, three of which demonstrated a statistical superiority over placebo.

Escitalopram appears effective in treating social anxiety disorder as well.

Escitalopram is effective in reducing the symptoms of premenstrual syndrome, whether taken continuously or in the luteal phase only.

Escitalopram has not been shown to affect serial reaction time, logical reasoning, serial subtraction, multitask, or Mackworth Clock task performance.

Escitalopram should be taken with caution when using St John's wort, ginseng, dextromethorphan, linezolid, tramadol, and other serotonergic drugs due to the risk of serotonin syndrome.

Escitalopram is the -stereoisomer of the racemate citalopram, which is responsible for its name: escitalopram.

Escitalopram was developed in close cooperation between Lundbeck and Forest Laboratories.

Escitalopram is sold under many brand names worldwide such as Cipralex, Lexapro, Lexam, Mozarin, Aciprex, Depralin, Ecytara, Elicea, Nexpram, Pramatis, and Betesda.