1. Fernando Muslera has played in five Copa America tournaments, winning the title in 2011, and played every minute in goal for Uruguay as the country's undisputed number one in the 2010,2014, and 2018 FIFA World Cups, helping his nation to fourth place in the 2010 edition.
Fernando Muslera remained as the second-choice for the remainder of the season, making only four more Serie A appearances and none in the UEFA Champions League.
Fernando Muslera played 33 league matches out of 34 with Galatasaray, who retained their league title.
On 3 November 2013, Fernando Muslera suffered a fractured toe and therefore missed three Super Lig and two Champions League matches.
Fernando Muslera played 31 matches as Galatasaray regained their league title, but was absent in their cup final victory over Bursaspor due to his commitments for the 2015 Copa America.
On 27 February 2021, Fernando Muslera played his 300th league match for Galatasaray against BB Erzurumspor, breaking the appearances record for a foreign player in the Super Lig.
Fernando Muslera, played his 429th match in the Super Lig with Galatasaray on January 25,2025, became the Galatasaray player who has played the most in the history of the Super Lig.
On 13 December 2021, in an away league match against Sivasspor, Fernando Muslera collided with his teammate Christian Luyindama in his box and was left writhing in pain.
Galatasaray stated that the collision had torn the medial collateral ligament on Fernando Muslera's left knee and hurt the anterior cruciate ligament.
Fernando Muslera made his World Cup debut against France on 11 June 2010, Uruguay's opening match of the tournament.
Fernando Muslera kept a clean sheet during all three of Uruguay's group matches.
Fernando Muslera was decisive in the quarter-final match against Ghana, where he saved two penalties at the penalty shootout.
Fernando Muslera was a key component of the Uruguay team that reached the semi-finals of the World Cup and subsequently finished fourth in the tournament.
Fernando Muslera was called again by coach Oscar Tabarez to represent Uruguay as the first-choice goalkeeper at the 2011 Copa America, held in Argentina.
Fernando Muslera was selected man of the match in the quarter-final against Argentina in which Uruguay progressed on penalties, with Muslera saving a penalty from Carlos Tevez to win the match.
Fernando Muslera started every game and played in every minute of Uruguay's successful cup campaign.
Fernando Muslera was Uruguay's first-choice goalkeeper at the 2014 World Cup and the 2015 Copa America, playing every minute as Uruguay reached the last 16 of the former and the quarter-finals of the latter.
Fernando Muslera similarly featured in all of Uruguay's games at the Copa America Centenario the following year, where they suffered a first round elimination.
In May 2018 Fernando Muslera was named in Uruguay's provisional 26-man squad for the 2018 FIFA World Cup in Russia.
On 25 April 2024, Fernando Muslera announced his retirement from the national team.
An acrobatic goalkeeper, Fernando Muslera is mainly known for his excellent shot-stopping and ability in the air.