Furosemide is a loop diuretic medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
| FactSnippet No. 2,557,602 |
10 Facts About Furosemide
2.
Furosemide is a type of loop diuretic that works by decreasing the reabsorption of sodium by the kidneys.
| FactSnippet No. 2,557,603 |
3.
Furosemide was patented in 1959 and approved for medical use in 1964.
| FactSnippet No. 2,557,604 |
4.
Furosemide is primarily used for the treatment of edema, but in some cases of hypertension.
| FactSnippet No. 2,557,605 |
5.
Furosemide is used for liver cirrhosis, kidney impairment, nephrotic syndrome, in adjunct therapy for swelling of the brain or lungs where rapid diuresis is required, and in the management of severe hypercalcemia in combination with adequate rehydration.
| FactSnippet No. 2,557,606 |
6.
Furosemide is mainly excreted by tubular secretion in the kidney.
| FactSnippet No. 2,557,607 |
7.
Furosemide is a known ototoxic agent generally causing transient hearing loss but can be permanent.
| FactSnippet No. 2,557,608 |
8.
Furosemide has been reported to reversibly antagonize GABA-evoked currents of a6ß2?2 receptors at µM concentrations, but not a1ß2?2 receptors.
| FactSnippet No. 2,557,609 |
9.
Furosemide is used in horses for pulmonary edema, congestive heart failure, and allergic reactions.
| FactSnippet No. 2,557,610 |
10.
Furosemide should be used with caution when combined with corticosteroids, aminoglycoside antibiotics, and trimethoprim sulfa.
| FactSnippet No. 2,557,611 |