1. George Stark was born on 1933 and is an American chemist and biochemist.
22 Facts About George Stark
1. 2.
George Stark's father, Jack Stark, was a restaurant owner, and his mother, Florence Stark, was a bookkeeper.
3.
George Stark was the youngest of three children, with two older sisters, Edna and Bernyce.
4.
The family remained there until George Stark was through his third year of high school, after which they relocated back to New York City, NY in 1950.
5.
George Stark met his wife, Mary Beck, during his undergraduate years, and the two married shortly after they both graduated.
6.
George Stark then went on to attend the Bronx High School of Science for his final year.
7.
George Stark went on to receive his undergraduate and graduate degrees from Columbia College of Columbia University.
8.
George Stark received his undergraduate degree in 1955 and his Ph.
9.
George Stark began his undergraduate studies as a premedical student but changed his path after having difficulty with a comparative anatomy course.
10.
George Stark's graduate studies were in the field of chemistry, and he did his research in the lab of Charles Dawson, who was a professor of organic chemistry and biochemistry.
11.
George Stark then completed a postdoctoral fellowship at Rockefeller University, where he did extensive research involving different enzymes.
12.
In 1992, to avoid ICRF mandated retirement, George Stark returned to the United States to continue his research.
13.
George Stark settled in Cleveland, Ohio, where he worked as a chairman at the Cleveland Clinic Foundation, where he helped expand the Lerner Research Institute from 1992 to 2002.
14.
George Stark later served as a chair of the advisory committee at the Center for Gene Regulation in Health and Disease at Cleveland State University, and he assisted in development of the Cellular and Molecular Medicine Specialization program that was jointly offered by Cleveland State University and the Lerner Research Institute.
15.
George Stark is currently continuing his research in Cancer Biology at the Cleveland Clinic Foundation.
16.
George Stark is the author of over 250 publications and has worked alongside several Nobel Laureates.
17.
In graduate school at Columbia, George Stark investigated ascorbic acid oxidase, which was concentrated in the skin of yellow crook-necked squash, and focused specifically on the role of its sulfhydryl groups.
18.
George Stark did significant work with cyanate, which can be produced from urea.
19.
George Stark's experiments set out to explain why enzymatic activity, namely of ribonuclease, decreased when in solution with urea.
20.
George Stark then conducted several experiments to evaluate his hypothesis using various proteins and urea.
21.
George Stark's research was now focused on aspartate transcarbamylase, which catalyzes the transfer of a carbamyl group from phosphate to aspartate, and he and his colleague Kim Collins investigated a certain intermediate of this reaction, namely N-phosphonacetyl-l-aspartate, better known as PALA.
22.
Furthermore, with another colleague Randall Johnson, George Stark began testing the use of PALA as a treatment for tumors in mice cells, with significant rudimentary results.