12 Facts About Ibogaine

Ibogaine is a naturally occurring psychoactive substance found in plants in the family Apocynaceae such as Tabernanthe iboga, Voacanga africana, and Tabernaemontana undulata.

Ibogaine is used to facilitate psychological introspection and spiritual exploration.

Ibogaine-containing preparations are used for medicinal and ritual purposes within the African spiritual traditions of the Bwiti, who claim to have learned it from the Pygmy peoples.

Ibogaine is an indole alkaloid that is obtained either by extraction from the iboga plant or by semi-synthesis from the precursor compound voacangine, another plant alkaloid.

Ibogaine is derived from the root of the Tabernanthe iboga, a plant known to exhibit psychedelic effects in its users.

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Ibogaine is sometimes administered per rectum to avoid nausea and vomiting.

Ibogaine is available in a total alkaloid extract of the Tabernanthe iboga plant, which contains all the other iboga alkaloids and thus has only about half the potency by weight of standardized ibogaine hydrochloride.

Ibogaine was first isolated from T iboga in 1901 by Dybowski and Landrin and independently by Haller and Heckel in the same year using T iboga samples from Gabon.

Ibogaine contracted with a Belgian company to produce ibogaine in tablet form for clinical trials in the Netherlands, and was awarded a United States patent for the product in 1985.

Ibogaine and related indole compounds are susceptible to oxidation over time.

Ibogaine has been reported in multiple small-study cohorts to reduce cravings for methamphetamine.

Ibogaine has been used as an adjunct to psychotherapy by Claudio Naranjo, documented in his book The Healing Journey.