17 Facts About Isabella Karle

Isabella Helen Karle was an American chemist who was instrumental in developing techniques to extract plutonium chloride from a mixture containing plutonium oxide.

Isabella Karle Helen Lugoski was born in Detroit, Michigan, on December 2,1921, the daughter of immigrants from Poland.

Isabella Karle attended the local public schools and skipped two grades in elementary school, despite not speaking English until the first grade.

Isabella Karle drew inspiration from a biography of Marie Curie.

Isabella Karle attended Wayne University in Detroit for a semester before obtaining a four-year scholarship to the University of Michigan, where she majored in physical chemistry and received a Bachelor of Science at age 19, followed by Master of Science and Ph.

Isabella Karle worked on the Manhattan Project during World War II, where she developed techniques to extract plutonium chloride from a mixture containing plutonium oxide.

Isabella Karle joined the United States Naval Research Laboratory after the end of the war.

Isabella Karle was the first person to apply the method.

Isabella Karle developed the symbolic addition procedure that connects the theoretical "direct method" apparatus and actual X-ray diffraction data.

In 1985, Jerome Karle was awarded the Nobel Prize in Chemistry, together with mathematician Herbert A Hauptman, for developing direct methods for analyzing X-ray diffraction data.

The Nobel Committee ignored Isabella's crucial role in solving the problem in practice, and Jerome Karle and many other members of the crystallography community strongly believed that Isabella Karle should have shared the prize.

Isabella Karle was the first to publish the structures of many important molecules and received many honors.

Isabella Karle was elected a Fellow of the National Academy of Sciences and the American Academy of Arts and Sciences.

Isabella Karle was elected to the American Philosophical Society in 1992.

Isabella Karle died on October 3,2017, at a hospice in Alexandria, Virginia at 95 from a brain tumor.

Isabella Karle was exposed to radiation during her work on the Manhattan project.

Isabella Karle was married to Jerome Isabella Karle, with whom she had three daughters, all of whom work in scientific fields:.