15 Facts About Ivermectin

Ivermectin is used to treat human diseases caused by roundworms and ectoparasites.

Ivermectin is the primary treatment for Mansonella ozzardi and cutaneous larva migrans.

Ivermectin is sometimes added to albendazole or mebendazole for whipworm treatment, and is considered a second-line treatment for gnathostomiasis.

Ivermectin is used to treat rosacea and blepharitis, both of which can be caused or exacerbated by Demodex folliculorum mites.

Ivermectin is secreted in very low concentration in breast milk.

Ivermectin is considered relatively free of toxicity in standard doses .

Ivermectin is routinely used to control parasitic worms in the gastrointestinal tract of ruminant animals.

Ivermectin is only effective in killing some of these parasites, this is because of an increase in anthelmintic resistance.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray.

Ivermectin is safe for mammals because mammalian glutamate-gated chloride channels only occur in the brain and spinal cord: the causative avermectins usually do not cross the blood–brain barrier, and are unlikely to bind to other mammalian ligand-gated channels.

Ivermectin earned the title of "wonder drug" for the treatment of nematodes and arthropod parasites.

Ivermectin has been used safely by hundreds of millions of people to treat river blindness and lymphatic filariasis.

Ivermectin donated hundreds of millions of courses of treatments since 1988 in more than 30 countries.

Ivermectin has been researched in laboratory animals, as a potential treatment for trichinosis.

Ivermectin is of interest in the prevention of malaria, as it is toxic to both the malaria plasmodium itself and the mosquitos that carry it.