15 Facts About Ivermectin


Ivermectin is used to treat human diseases caused by roundworms and ectoparasites.

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Ivermectin is the primary treatment for Mansonella ozzardi and cutaneous larva migrans.

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Ivermectin is sometimes added to albendazole or mebendazole for whipworm treatment, and is considered a second-line treatment for gnathostomiasis.

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Ivermectin is used to treat rosacea and blepharitis, both of which can be caused or exacerbated by Demodex folliculorum mites.

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Ivermectin is secreted in very low concentration in breast milk.

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Ivermectin is considered relatively free of toxicity in standard doses .

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Ivermectin is routinely used to control parasitic worms in the gastrointestinal tract of ruminant animals.

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Ivermectin is only effective in killing some of these parasites, this is because of an increase in anthelmintic resistance.

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Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray.

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Ivermectin is safe for mammals because mammalian glutamate-gated chloride channels only occur in the brain and spinal cord: the causative avermectins usually do not cross the blood–brain barrier, and are unlikely to bind to other mammalian ligand-gated channels.

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Ivermectin earned the title of "wonder drug" for the treatment of nematodes and arthropod parasites.

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Ivermectin has been used safely by hundreds of millions of people to treat river blindness and lymphatic filariasis.

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Ivermectin donated hundreds of millions of courses of treatments since 1988 in more than 30 countries.

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Ivermectin has been researched in laboratory animals, as a potential treatment for trichinosis.

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Ivermectin is of interest in the prevention of malaria, as it is toxic to both the malaria plasmodium itself and the mosquitos that carry it.

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