1. Javier Castillejo held multiple world championships in two weight classes, including the WBC and lineal light-middleweight titles from 1999 to 2001, the WBC light-middleweight title again in 2005, and the WBA middleweight title from 2006 to 2007.
Javier Castillejo had four more wins, before he was defeated for the first time.
On 10 April 1992, Javier Castillejo got his first win against a former or future world champion when he knocked out former IBF lightweight champion, Puerto Rican Harry Arroyo, in three rounds at Leganes.
Javier Castillejo defended the title successfully four times, then lost it, on 3 January 1995 to the then WBA light middleweight champion Laurent Boudouani, in Epernay, France, by knockout in the ninth round.
Javier Castillejo then won six more fights in a row before fighting for a world title again.
Javier Castillejo regained the EBU light middleweight title by knocking out the former WBA welterweight title challenger, Ahmed Dottuev, in round twelve at Suffolk, England, on 2 July 1998.
On 29 January 1999, Javier Castillejo got his second chance at becoming a world champion.
Javier Castillejo outpointed Lineal and WBC light middleweight champion Keith Mullings over twelve rounds to join a handful of world champions to come from Spain.
Javier Castillejo commented to this regard, saying on a press conference before the fight, which was held in Las Vegas, that " didn't come to Las Vegas to do tourism, but to defend title".
Javier Castillejo lasted the twelve round distance with De La Hoya, but was sent to the canvas seconds before the fight ended, and lost a unanimous twelve-round decision and his world title, on 23 June 2001.
Javier Castillejo then won four fights in a row, all by knockout.
Javier Castillejo fought Fernando Vargas, in a fight that was supposed to be for the WBA's vacant light middleweight title, on 20 August 2005, in Chicago.
On 15 July 2006, Javier Castillejo sprang back on the boxing scene by defeating younger Felix Sturm of Germany to seize the WBA middleweight belt in an exciting fight.
Sturm, making his first title defense, was headed to a one-sided win until Javier Castillejo caught him with a left hook against the ropes with 13 seconds left in the 10th Round.
Javier Castillejo, then hit Sturm with three uppercuts before the referee called the fight, making Javier Castillejo, 38 at the time of his upset victory, the oldest man to win a recognized version on the World Middleweight Championship.
Javier Castillejo lost his title in his first defence against Argentine Mariano Natalio Carrera via a disputed 11th-round TKO.
Javier Castillejo lost the title 28 April 2007 in a rematch against Felix Sturm.
Javier Castillejo fought Mariano Natalio Carrera again on 13 November 2007, this time winning by KO in the 6th round.