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17 Facts About Julius Youngner

1.

Julius Youngner is considered "one of the seminal figures in contemporary virology and it's been that way for more than 50 years" by Arthur S Levine, senior vice chancellor for the health sciences at University of Pittsburgh.

2.

Julius Youngner was an important early pioneer in vaccine development, testing, and government licensing of drugs before allowing them to market.

3.

Julius Youngner was critical of Cutter Laboratories virus manufacturing prior to deaths resulting from Cutter inactivated vaccine.

4.

Julius Youngner continued to promote research integrity and actions on misconduct until the end of his career.

5.

When he was seven-years-old Julius Youngner was nearly killed by lobar pneumonia.

6.

Julius Youngner never knew the research was related to weapons until the end of the war.

7.

Julius Youngner thought nuclear energy would be used for planes or submarines for transportation.

8.

In 1949, Julius Youngner moved to the University of Pittsburgh to pursue virology at and, subsequently, to the University of Pittsburgh School of Medicine for the rest of his career.

9.

Julius Youngner proved a method for separation of monkey kidney cells, which led to techniques for large scale production.

10.

Julius Youngner developed a process to prevent infection while retaining ability to vaccinate, and 3.

11.

Julius Youngner demonstrated the separation of monkey kidney cells using the pancreatic enzyme trypsin, a technique previously proven by the Rockefeller Institute could be applied to high titer virus stocks.

12.

Julius Youngner identified that a difference in pH, as indicated by metabolic activity by other researchers, could be used to identify cell cultures infected with virus and cultures with antibodies to virus.

13.

The key to effective inactivation depended upon a color test developed by Julius Youngner, which allowed formalin induced viral protein degradation to be accurately plotted.

14.

Julius Youngner's team studied the mechanisms of these infections, and infections of vesicular stomatitis virus, sendai virus, and persistent newcastle disease virus.

15.

Julius Youngner is responsible for the first equine influenza vaccine, based upon cold-adapted influenza virus.

16.

Julius Youngner has contributed patents on Lipid purification and concentration of viruses and vaccines, an important contribution to the reduction of egg protein and associated vaccine induced complications, antitumor processes of Brucella, and numerous contributions to cold adapted influenza virus.

17.

Julius Youngner met and married his first wife, Tula Liakakis, in Michigan, in 1943.