1. Kaniehtiio Horn was nominated for a Gemini Award for her role in the television film Moccasin Flats: Redemption and she has appeared in the films The Trotsky, Leslie, My Name Is Evil, and The Wild Hunt, as well as the streaming television horror series Hemlock Grove and the sitcoms 18 to Life, Letterkenny and Reservation Dogs.
Kaniehtiio Horn was born in Ottawa and grew up in Ottawa and on the Kahnawake Mohawk reserve outside of Montreal.
Kaniehtiio Horn's mother, Kahn-Tineta Horn, is a Mohawk former model and a political activist for the Kahnawake First Nation.
Kaniehtiio Horn's father, who is of German and Scottish descent, is a lawyer.
Waneek was stabbed in the chest by a soldier wielding a bayonet while holding Kaniehtiio Horn, who was then aged four; a photograph of the incident, published on the front page of newspapers, symbolized the standoff between Mohawks and the Canadian government.
Kaniehtiio Horn decided to be an actress at a young age, but concentrated on swimming and water polo as a teenager.
Kaniehtiio Horn graduated from Dawson College in 2005 for theatre arts, and appeared in a number of short films.
Kaniehtiio Horn landed a role in the 2007 drama film The Colony, directed by Jeff Barnaby.
Kaniehtiio Horn appeared in Journey to the Center of the Earth that year, starring Brendan Fraser.
In 2009, Kaniehtiio Horn starred in The Trotsky, directed by Jacob Tierney, playing a Montreal high school student.
Kaniehtiio Horn appeared in The Wild Hunt, directed by Alexandre Franchi and in Reginald Harkema's Leslie, My Name Is Evil as a member of Charles Manson's death cult.
Kaniehtiio Horn starred in the CBC television sitcom 18 to Life as Monica Bellow.
Kaniehtiio Horn voiced several roles in By the Rapids, an APTN cartoon which she had made in collaboration with Joseph Tekaroniake Lazare.
Kaniehtiio Horn shot an APTN television pilot, Escape Hatch, with Mohawk writer-director Tracey Deer.
In 2010, Kaniehtiio Horn again worked with Jacob Tierney in the film Good Neighbours.
Kaniehtiio Horn starred in the low-budget slasher film A Flesh Offering, directed by Jeremy Torrie, playing an artist who gets lost in the woods.
In 2011, Kaniehtiio Horn starred in the horror anthology film The Theatre Bizarre, and played a priestess in Immortals.
Kaniehtiio Horn filmed Penthouse North with Michelle Monaghan and Michael Keaton and shot a CBC comedy pilot.
In 2012, Kaniehtiio Horn joined the cast of the Netflix drama Hemlock Grove as Destiny Rumancek, a Romani witch.
Kaniehtiio Horn starred opposite Famke Janssen, Dougray Scott, Bill Skarsgard, Landon Liboiron and Lili Taylor in the series.
Kaniehtiio Horn voiced the role of Kaniehti:io, the Native American protagonist's Mohawk mother, in the 2012 video game Assassin's Creed III, developed by Ubisoft.
In 2013, Kaniehtiio Horn played Rynn, an Irathient Spirit Rider, on the Syfy TV series, Defiance, and played Dorothy from The Wizard of Oz in "Slumber Party", an episode of the CW series Supernatural.
Kaniehtiio Horn appeared in Embrace of the Vampire starring Sharon Hinnendael, a remake of the 1995 horror film of the same name, in the television special Gavin Crawford's Wild West and in the Amazon series The Man in the High Castle.
Kaniehtiio Horn appeared in a recurring role as Tanis in the CraveTV series Letterkenny, for which she won the Canadian Screen Award for Best Supporting Actress in a Comedy Series at the 10th Canadian Screen Awards in 2022.
Kaniehtiio Horn has taken up the role of Consulting Producer on the Letterkenny spinoff show Shoresy, where she was tasked with ensuring the faithful portrayal of the show's many Indigenous characters.
In 2020, Kaniehtiio Horn appeared as a panelist on Canada Reads advocating for Eden Robinson's novel Son of a Trickster.
In 2022, Kaniehtiio Horn appeared in a recurring role as Feather Day in season 2 of the Peacock series, Rutherford Falls.
Kaniehtiio Horn gave birth to a son via emergency C-section in November 2020.