11 Facts About Karen Vousden

1.

Karen Vousden is known for her work on the tumour suppressor protein, p53, and in particular her discovery of the important regulatory role of Mdm2, an attractive target for anti-cancer agents.

2.

Karen Vousden served on the Life Sciences jury for the Infosys Prize in 2014.

3.

Karen Vousden was part of a group which showed that E6, one of the HPV-16 oncoproteins, binds to the human tumour suppressor protein p53 in vivo, resulting in its degradation.

4.

Karen Vousden's work has been important in delineating the mechanism of this process.

5.

Karen Vousden discovered that a key element in this regulation is the protein Mdm2.

6.

Karen Vousden's group have recently discovered a novel p53-regulated protein, TIGAR, which can reduce oxidative stress in cells and might mediate part of this effect of p53.

7.

Karen Vousden is a fellow of the Royal Society, Royal Society of Edinburgh and the Academy of Medical Sciences ; she was elected a member of the European Molecular Biology Organization in 2004.

8.

Karen Vousden gave the Sir Frederick Gowland Hopkins Memorial Lecture of the Biochemical Society in 2008.

9.

Karen Vousden was awarded the Royal Medal from the Royal Society of Edinburgh in 2009.

10.

Karen Vousden was appointed Commander of the Order of the British Empire in the 2010 New Year Honours.

11.

In 2021, Karen Vousden was recognized with the first Pezcoller Foundation-Marina Larcher Fogazzaro-EACR Women in Cancer Award.