Lisinopril is a medication of the angiotensin-converting enzyme inhibitor and is used to treat high blood pressure, heart failure, and after heart attacks.
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Lisinopril is a medication of the angiotensin-converting enzyme inhibitor and is used to treat high blood pressure, heart failure, and after heart attacks.
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Lisinopril was patented in 1978 and approved for medical use in the United States in 1987.
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Lisinopril has a proline group that is responsible for the availability of the drug in oral formulation.
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Lisinopril is typically used for the treatment of high blood pressure, congestive heart failure, and diabetic nephropathy and after acute myocardial infarction .
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Lisinopril is started at 5 or 10 mg and titrated upwards to 40 mg once daily maximum.
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Lisinopril is contraindicated in people who have a history of angioedema or who have diabetes and are taking aliskiren.
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Lisinopril is an ACE inhibitor, meaning it blocks the actions of angiotensin-converting enzyme in the renin–angiotensin–aldosterone system, preventing angiotensin I from being converted to angiotensin II.
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Lisinopril absorption is not affected by the presence of food in the gastrointestinal tract.
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Lisinopril is the only water-soluble member of the ACE inhibitor class, with no metabolism by the liver.
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Lisinopril is soluble in water, less soluble in methanol, and virtually insoluble in ethanol.
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