Lucy Shapiro is a professor of Developmental Biology at the Stanford University School of Medicine.
26 Facts About Lucy Shapiro
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Lucy Shapiro's work has furthered understanding of the basis of stem cell function and the generation of biological diversity.
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Lucy Shapiro's ideas have revolutionized understanding of bacterial genetic networks and helped researchers to develop novel drugs to fight antibiotic resistance and emerging infectious diseases.
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In 2013, Lucy Shapiro was presented with the 2011 National Medal of Science.
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Lucy Shapiro was born in Brooklyn, New York City, the eldest of three daughters.
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Lucy Shapiro's mother was an elementary school teacher and her father, a Ukrainian immigrant.
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Lucy Shapiro attended New York City's High School of Music and Arts with a major in Fine Arts.
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Lucy Shapiro enrolled in Brooklyn College with a double major in Fine Arts and Biology and the intention of becoming a medical illustrator.
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In fall 1962 Shapiro was hired as a lab technician by J Thomas August and Jerard Hurwitz in the Department of Microbiology at the New York University School of Medicine.
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Lucy Shapiro was given the task of looking for RNA-dependent RNA polymerase using F2 RNA phage from Norton Zinder.
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Lucy Shapiro was successful in detecting the activity of an enzyme copying RNA.
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In 1963 Lucy Shapiro became a graduate student at NYU with Tom August as her advisor.
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Lucy Shapiro attended summer courses at Cold Spring Harbor Laboratory on Long Island.
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Lucy Shapiro has published reflections on her early days in Brooklyn and on her life in science in the Journal of Biological Chemistry and in the Annual Review of Genetics.
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Lucy Shapiro initially planned to do postdoctoral work elsewhere, but was offered a faculty position at Einstein by Bernard Horecker.
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Lucy Shapiro identified positional information as a key research area, asking how spatial information is genetically encoded and translated, to create the three-dimensional organization of a cell and to form different daughter cells through cell division.
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In 1989, Lucy Shapiro became a Professor and the Founding Chair of the Department of Developmental Biology at Stanford University School of Medicine, Stanford, CA.
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In 2001 Lucy Shapiro became the Director of the Beckman Center for Molecular and Genetic Medicine at Stanford University School of Medicine.
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Lucy Shapiro wanted to go beyond test-tube studies of extracted cell contents, and examine the three-dimensional structure and behavior of actual living cells.
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Lucy Shapiro was the first researcher to show that bacterial DNA replication occurs in a spatially organized way and that cell division is dependent on this spatial organization.
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In 2004, using time-lapse microscopy and fluorescent tags, Lucy Shapiro demonstrated that chromosomal regions are duplicated in both an orderly and a location-specific manner, involving "a much higher degree of spatial organization than previously thought".
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In 2002, Lucy Shapiro founded Anacor Pharmaceuticals with physicist and developmental biologist Harley McAdams and chemist Stephen Benkovic of Pennsylvania State University.
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Lucy Shapiro has advised both the Clinton administration and the second Bush administration.
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Lucy Shapiro belongs to the Center for International Security and Cooperation at the Freeman Spogli Institute for International Studies at Stanford University.
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Lucy Shapiro is particularly concerned about the potential impact of emerging infectious diseases.
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Lucy Shapiro is involved in development of drugs that will attack both a particular bacteria and its mechanisms of drug resistance, to prevent drug-resistant strains from developing.