10 Facts About Lymph node

Lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system.

Each lymph node is surrounded by a fibrous capsule, which extends inside a lymph node to form trabeculae.

The substance of a lymph node is divided into the outer cortex and the inner medulla.

Lymph node is divided into compartments called nodules, each consisting of a region of cortex with combined follicle B cells, a paracortex of T cells, and a part of the nodule in the medulla.

The substance of a lymph node is divided into the outer cortex and the inner medulla.

The cortex of a lymph node is the outer portion of the node, underneath the capsule and the subcapsular sinus.

Lymph node contains lymphoid tissue, i e, a meshwork or fibers called reticulum with white blood cells enmeshed in it.

The lymph node capsule is composed of dense irregular connective tissue with some plain collagenous fibers, and a number of membranous processes or trabeculae extend from its internal surface.

Lymph node is present throughout the body, and circulates through lymphatic vessels.

Lymph node involvement is often a key part in the diagnosis and treatment of cancer, acting as "sentinels" of local disease, incorporated into TNM staging and other cancer staging systems.