14 Facts About Manolis Kellis

Manolis Kellis is a professor of Computer Science and Computational Biology at the Massachusetts Institute of Technology and a member of the Broad Institute of MIT and Harvard.

Manolis Kellis is the head of the Computational Biology Group at MIT and is a Principal Investigator in the Computer Science and Artificial Intelligence Lab at MIT.

Manolis Kellis co-led the NIH Roadmap Epigenomics Project effort to create a comprehensive map of the human epigenome, the comparative analysis of 29 mammals to create a comprehensive map of conserved elements in the human genome, the ENCODE, GENCODE, and modENCODE projects to characterize the genes, non-coding elements, and circuits of the human genome and model organisms.

Manolis Kellis was born in Greece, moved with his family to France when he was 12, and came to the US in 1993.

Manolis Kellis obtained his PhD from MIT, where he worked with Eric Lander, founding director of the Broad Institute, and Bonnie Berger, professor at MIT and received the Sprowls award for the best doctorate thesis in Computer Science, and the first Paris Kanellakis graduate fellowship.

Manolis Kellis has helped direct several large-scale genomics projects, including the Roadmap Epigenomics project, the Encyclopedia of DNA Elements project, the Genotype Tissue-Expression project.

Manolis Kellis started comparing the genomes of yeast species as an MIT graduate student.

Manolis Kellis turned from yeast to flies and ultimately to mammals, comparing multiple species to explore genes, their control elements, and their deregulation in human disease.

Manolis Kellis led several comparative genomics projects in human, mammals, flies, and yeast.

Manolis Kellis co-led the NIH government-funded project to catalogue the human epigenome.

The Manolis Kellis Lab has profiled a large number of human post-mortem brains at single-cell resolution, studying inter-individual variation associated with genetic differences and disease phenotypes, including the first single-cell transcriptomic analysis of Alzheimer's disease.

Manolis Kellis is a member of the Genotype-Tissue Expression project that seeks to elucidate the basis of disease predisposition.

Manolis Kellis is a Principal Investigator of the enhancing GTEx consortium, studying epigenomic changes of regulatory elements and epitranscriptomic changes of RNA transcripts across multiple human tissues.

Manolis Kellis was named as one of Technology Review's Top 35 Innovators Under 35 for his research in comparative genomics.