23 Facts About Margaret Robinson

Margaret Scott Robinson was born on 1951 and is a British molecular cell biologist, a professor and researcher in the Cambridge Institute for Medical Research, at the University of Cambridge.

Margaret Robinson completed her PhD at Harvard University supervised by David Albertini and Barbara Pearse.

Margaret Robinson was first exposed about science early in her life from reading about Marie Curie.

However, due to university requirements, Margaret Robinson had to complete an introductory biology course.

Margaret Robinson eventually joined a new lab and was able to conduct research on anything she liked.

Margaret Robinson had to stop working on her interest in coated vesicles and work on something closer to what the lab was researching.

Margaret Robinson eventually started a postdoctoral research with Barbara Pearse, joining her at the MRC Laboratory of Molecular Biology in December 1982.

Margaret Robinson's interest was in clathrin-coated vesicles that binds to cargo.

Margaret Robinson eventually succeeded in purifying components of the coat that were not clathrin and are now known as adaptor proteins.

Continuing, Margaret Robinson discovered that there were two different populations of clathrin-coated vesicles, one that uses AP-2 at the plasma membrane and one that uses AP-1 and was associated with intracellular membranes.

Margaret Robinson's achievements include the discovery of adaptins, which are specific proteins that manage cell-trafficking to ensure the correct cell cargo is transported to the right location.

Margaret Robinson discovered different combinations of adapting, when together with clathrin, form a coat around vesicles that bud from intracellular membranes and act as transporters for protein packages to be distributed in the cell.

Margaret Robinson's main focus was to learn more about the AP protein in depth.

Margaret Robinson had to work with DNA because in order to characterize the complexes thoroughly, she needed to clone the subunits.

Margaret Robinson's working hypothesis is that for each trafficking pathway, there are a number of different adaptors, each of which is recruited independently onto the appropriate membrane.

Margaret Robinson's laboratory uses many techniques including immunolocalisation at the light and electron microscope levels, sub cellular fractionation, protein purification, proteomics, flow cytometry, live cell imaging, and X-ray crystallography.

Margaret Robinson's work is speculated to play a key role in evolution of eukaryotes form prokaryotes over two billion years ago.

Margaret Robinson's work explains how coated vesicles sort cargo but provides tools that can be used by others to address their own favorite problems.

Margaret Robinson's technique has found its way into other labs who are interested in how particular proteins contribute to different stages of cell division.

Margaret Robinson has received many honors working as a cellular biologist.

Margaret Robinson was awarded a Wellcome Trust Principal Research Fellowship in 1999 and in 2003 she was appointed Professor of Molecular Cell Biology.

Margaret Robinson was elected a Fellow of the Academy of Medical Sciences and member of the European Molecular Biology Organization.

Margaret Robinson was elected a Fellow of the Royal Society in 2012.