16 Facts About Memory consolidation

Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition.

The first, synaptic Memory consolidation, which is thought to correspond to late-phase long-term potentiation, occurs on a small scale in the synaptic connections and neural circuits within the first few hours after learning.

The second process is systems Memory consolidation, occurring on a much larger scale in the brain, rendering hippocampus-dependent memories independent of the hippocampus over a period of weeks to years.

Memory consolidation was first referred to in the writings of the renowned Roman teacher of rhetoric Quintillian.

Synaptic consolidation is one form of memory consolidation seen across all species and long-term memory tasks.

Standard model of synaptic Memory consolidation suggests that alterations of synaptic protein synthesis and changes in membrane potential are achieved through activating intracellular transduction cascades.

Systems Memory consolidation is a slow dynamic process that can take anywhere from one to two decades to be fully formed in humans, unlike synaptic Memory consolidation that only takes minutes to hours for new information to stabilize into memories.

Standard model of systems consolidation has been summarized by Squire and Alvarez ; it states that when novel information is originally encoded and registered, memory of these new stimuli becomes retained in both the hippocampus and cortical regions.

Memory consolidation is retained in the hippocampus for up to one week after initial learning, representing the hippocampus-dependent stage.

The BLA is thought to be actively involved in memory consolidation and is influenced strongly by stress hormones resulting in increased activation and as such increased memory retention.

Once memories undergo the process of consolidation and become part of long-term memory, they are thought of as stable.

Memory consolidation modification needs to be demonstrated in the retrieval in order for this independent process to be valid.

Theory of reMemory consolidation has been debated for many years and is still controversial.

ReMemory consolidation was first conceptualized in light of the discovery that phobias could often be eliminated by means of electroconvulsive shock therapy.

The rats that were injected with anisomycin after Memory consolidation had taken place, retained the fear reaction to the tone.

Questions arose if reMemory consolidation was a unique process or merely another phase of Memory consolidation.