Nitroglycerin has been used for over 130 years in medicine as a potent vasodilator to treat heart conditions, such as angina pectoris and chronic heart failure.
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14 Facts About Nitroglycerin
2.
Nitroglycerin is available in sublingual tablets, sprays, ointments, and patches.
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3.
Nitroglycerin was the first practical explosive produced that was stronger than black powder.
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4.
Nitroglycerin was later adopted as a commercially useful explosive by Alfred Nobel, who experimented with safer ways to handle the dangerous compound after his younger brother, Emil Oskar Nobel, and several factory workers were killed in an explosion at the Nobels' armaments factory in 1864 in Heleneborg, Sweden.
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5.
Nitroglycerin began treating his patients with small diluted doses of nitroglycerin in 1878, and this treatment was adopted into widespread use after Murrell published his results in the journal The Lancet in 1879.
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6.
Nitroglycerin can be produced by acid-catalyzed nitration of glycerol .
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7.
Nitroglycerin named this explosive dynamite and patented it in 1867.
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8.
Nitroglycerin was used as an ingredient in military propellants for use in firearms.
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9.
Nitroglycerin has been used in conjunction with hydraulic fracturing, a process used to recover oil and gas from shale formations.
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10.
Nitroglycerin has an advantage over some other high explosives that on detonation it produces practically no visible smoke.
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11.
Nitroglycerin belongs to a group of drugs called nitrates, which includes many other nitrates like isosorbide dinitrate and isosorbide mononitrate .
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12.
Nitroglycerin corrects the imbalance between the flow of oxygen and blood to the heart and the heart's energy demand.
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13.
Nitroglycerin is available in tablets, ointment, solution for intravenous use, transdermal patches, or sprays administered sublingually.
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14.
Nitroglycerin was first used by William Murrell to treat angina attacks in 1878, with the discovery published that same year.
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