11 Facts About Paul Negulescu

Paul Negulescu is a Senior Vice President at American pharmaceutical company Vertex Pharmaceuticals.

Paul Negulescu received the 2022 Shaw Prize in Life science and medicine, together with Michael J Welsh, for their work that uncovered the etiology of cystic fibrosis and developed effective medications.

Paul Negulescu's father was a surgeon, and his grandfather, Constantin Visoianu, was a former Minister of Foreign Affairs of Romania.

Paul Negulescu then went on and studied PhD in physiology under Terry Machen, completing it in 1990.

Paul Negulescu started his career as a postdoctoral researcher at the University of California, Berkeley and under Michael Cahalan at the University of California, Irvine.

Paul Negulescu was planning to move to the University of Connecticut when Roger Y Tsien asked him to join a startup company he was forming called Aurora Biosciences.

Paul Negulescu joined Aurora Biosciences in 1996 as one of the first employees.

Paul Negulescu became Senior Vice President of Discovery Biology in 1999.

Paul Negulescu has been leading the San Diego Research Center of Vertex Pharmaceuticals since 2003.

Paul Negulescu led the discovery of another cystic fibrosis drug, lumacaftor, which is known as a "corrector" as it acts as a chaperone to help the CFTR protein fold correctly.

Paul Negulescu met his wife, Debbie, during his time at the University of California, Irvine.