Pentobarbital is a short-acting barbiturate typically used as a sedative, a preanesthetic, and to control convulsions in emergencies.
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Pentobarbital is a short-acting barbiturate typically used as a sedative, a preanesthetic, and to control convulsions in emergencies.
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Pentobarbital was widely abused and sometimes known as "yellow jackets" due to the yellow capsule of the Nembutal brand.
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Pentobarbital was widely abused, known on the street as "yellow jackets".
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Pentobarbital can reduce intracranial pressure in Reye's syndrome, treat traumatic brain injury and induce coma in cerebral ischemia patients.
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Pentobarbital-induced coma has been advocated in patients with acute liver failure refractory to mannitol.
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Pentobarbital has been used or considered as a substitute for other drugs previously used for capital punishment in the United States when those drugs are unavailable.
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Pentobarbital undergoes first-pass metabolism in the liver and possibly the intestines.
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Pentobarbital is synthesized by methods analogous to that of amobarbital, the only difference being that the alkylation of a-ethylmalonic ester is carried out with 2-bromopentane in place of 1-bromo-3-methylbutane to give pentobarbital.
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Pentobarbital is the INN, AAN, BAN, and USAN while pentobarbitone is a former AAN and BAN.
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Pentobarbital can occur as a free acid, but is usually formulated as the sodium salt, pentobarbital sodium.
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