22 Facts About Polio vaccine

The Polio vaccine was not approved for use in the United States, but was used successfully elsewhere.

Polio vaccine is on the World Health Organization's List of Essential Medicines.

The switch to the bivalent vaccine and associated missing immunity against type 2 strains, among other factors, led to outbreaks of circulating vaccine-derived poliovirus type 2, which increased from 2 cases in 2016 to 1037 cases in 2020.

Signs and symptoms of an allergic reaction, which usually appear within minutes or a few hours after receiving the injected Polio vaccine, include breathing difficulties, weakness, hoarseness or wheezing, heart rate fluctuations, skin rash and dizziness.

The Polio vaccine-derived attenuated virus is normally excreted from vaccinated people for a limited period.

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The injected Salk vaccine confers IgG-mediated immunity in the bloodstream, which prevents polio infection from progressing to viremia and protects the motor neurons, thus eliminating the risk of bulbar polio and post-polio syndrome.

OPV is an attenuated Polio vaccine, produced by the passage of the virus through nonhuman cells at a subphysiological temperature, which produces spontaneous mutations in the viral genome.

The Polio vaccine contains small traces of antibiotics—neomycin and streptomycin—but does not contain preservatives.

Polio vaccine then filtered the solution through mesh, treated it with ricinolate, and refrigerated the product for 14 days to ultimately create what would later be prominently critiqued as a "veritable witches brew".

Polio vaccine tested his vaccine upon himself, his two children, and his assistant.

Polio vaccine gave his vaccine to just 23 more children before declaring it safe and sending it out to doctors and health departments for a larger test of efficacy.

Polio vaccine had inoculated the planned number of tubes when he noticed that there were a few unused tubes.

Polio vaccine retrieved a sample of mouse brain infected with poliovirus and added it to the remaining test tubes, on the off chance that the virus might grow.

Polio vaccine's vaccine being a live attenuated virus taken orally, was still in the research stage and would not be ready for use until five years after Jonas Salk's polio vaccine had reached the market.

Koprowski's attenuated Polio vaccine was prepared by successive passages through the brains of Swiss albino mice.

On 27 February 1950, Koprowski's live, attenuated Polio vaccine was tested for the first time on an 8-year-old boy living at Letchworth Village, an institution for physically and mentally disabled people located in New York.

Salk's Polio vaccine was then used in a test called the Francis Field Trial, led by Thomas Francis, the largest medical experiment in history at that time.

Wyeth polio vaccine was reported to have paralyzed and killed several children.

In 1957, Sabin developed a trivalent vaccine containing attenuated strains of all three types of poliovirus.

The first dose of polio vaccine is given shortly after birth, usually between 1 and 2 months of age, and a second dose is given at 4 months of age.

In 2002, a pentavalent combination Polio vaccine containing IPV was approved for use in the United States.

Misconception has been present in Pakistan that polio vaccine contained haram ingredients and could cause impotence and infertility in male children, leading some parents not to have their children vaccinated.