12 Facts About Proteins

1.

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

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2.

Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another.

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3.

Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity.

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4.

Proteins have structural or mechanical functions, such as actin and myosin in muscle and the proteins in the cytoskeleton, which form a system of scaffolding that maintains cell shape.

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5.

Proteins were recognized as a distinct class of biological molecules in the eighteenth century by Antoine Fourcroy and others, distinguished by the molecules' ability to coagulate or flocculate under treatments with heat or acid.

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6.

Proteins were first described by the Dutch chemist Gerardus Johannes Mulder and named by the Swedish chemist Jons Jacob Berzelius in 1838.

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7.

Proteins came to the erroneous conclusion that they might be composed of a single type of molecule.

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8.

Proteins can interact with many types of molecules, including with other proteins, with lipids, with carbohydrates, and with DNA.

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9.

Proteins are assembled from amino acids using information encoded in genes.

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10.

Proteins are the chief actors within the cell, said to be carrying out the duties specified by the information encoded in genes.

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11.

Proteins can bind to other proteins as well as to small-molecule substrates.

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12.

Proteins can bind to, or even be integrated into, cell membranes.

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