Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
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10 Facts About Quetiapine
2.
Quetiapine is believed to work by blocking a number of receptors including serotonin and dopamine.
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3.
Quetiapine was developed in 1985 and approved for medical use in the United States in 1997.
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4.
Quetiapine is primarily used to treat schizophrenia or bipolar disorder.
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5.
Quetiapine is effective when used by itself and when used along with other medications in major depressive disorder.
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6.
Quetiapine has fewer extrapyramidal side effects and is less likely to cause hyperprolactinemia when compared to other drugs used to treat schizophrenia, so is used as a first line treatment.
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7.
Quetiapine is excreted primarily via the kidneys and in feces after hepatic metabolism, the remainder is excreted as the drug in its unmetabolized form.
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8.
Quetiapine is a tetracyclic compound and is closely related structurally to clozapine, olanzapine, loxapine, and other tetracyclic antipsychotics.
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9.
Quetiapine has not provided a reason for the delay of Seroquel XR's launch.
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10.
Quetiapine received its initial indication from U S FDA for treatment of schizophrenia in 1997.
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