1. Reggie Lambe began his professional career with Ipswich Town, joining from Bermudian club Dandy Town Hornets, playing on the youth team and eventually joining the reserve squad, as well as making a first team appearance in a League Cup match against Shrewsbury Town.
Reggie Lambe made his league debut in Ipswich Town's victory over Middlesbrough at Riverside Stadium on 7 August 2010, replacing Carlos Edwards in the 64th minute.
Reggie Lambe joined Bristol Rovers on loan on 24 March 2011.
Reggie Lambe signed with Canadian club Toronto FC, of Major League Soccer, on 7 December 2011.
Reggie Lambe helped Toronto win the 2012 Canadian Championship with two goals, tying him with three other players for the Canadian Championship Golden Boot.
Reggie Lambe was put on waivers by Toronto FC on 5 March 2014.
Over three months, Reggie Lambe made twelve appearances for the club, scoring one goal before leaving.
Three days later, Reggie Lambe was named to the lineup as a substitute for Mansfield Town's league match against Carlisle United.
Reggie Lambe went on to debut for the club in the match, coming on as a 74th-minute substitute for Fergus Bell.
Reggie Lambe joined League Two rivals Carlisle United in June 2016.
On 28 June 2018 Reggie Lambe joined League Two club Cambridge United on a two-year contract.
Reggie Lambe left to join AFC Sudbury in February 2023.
On 29 June 2023, Reggie Lambe agreed to join National League South side, Braintree Town following a successful promotion campaign with AFC Sudbury.
On 27 September 2024, Reggie Lambe joined National League North side Needham Market.
In May 2019 Reggie Lambe was named to the 2019 CONCACAF Gold Cup squad ahead of Bermuda's first ever participation at the tournament.