Sheena Elizabeth Radford FRS FMedSci is a British biophysicist, and Astbury Professor of Biophysics in the Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology at the University of Leeds.
19 Facts About Sheena Radford
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Sheena Radford received her BSc in Biochemistry at the University of Birmingham in 1984, and her PhD in Biochemistry at the University of Cambridge in 1987.
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Sheena Radford completed a post-doctoral fellowship at the University of Oxford.
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Sheena Radford worked as a Lecturer in Biochemistry and Molecular Biology at the University of Leeds in 1995, progressing to Reader in 1998 and Professor in 2000.
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Sheena Radford became the Deputy Director of the Astbury Centre for Structural Molecular Biology in 2009 then Director in 2012.
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Sheena Radford's research investigates protein folding, protein aggregation and amyloid disease.
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In 2016, Sheena Radford received an Investigator Award in Science for Protein-protein interactions in the early stages of amyloid assembly mechanisms.
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Sheena Radford said that sequences will be uploaded to a database where advances in machine learning will eventually be able to identify patterns in protein sequences that can be scaled up for pharmaceutical production without needing any experiments.
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Sheena Radford's team tested whether these improved proteins would embed into artificial lipid membranes, finding that they could so efficiently without any accessory proteins.
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Sheena Radford was elected a Fellow of the Royal Society in 2014; her nomination reads:.
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Sheena Radford is internationally distinguished for her seminal contributions to understanding how the dynamical properties of proteins enable them to fold and function biologically, or to misfold and cause degenerative diseases.
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Sheena Radford has used sophisticated experimental techniques to characterise protein folding pathways in exquisite detail, in particular demonstrating that non-native as well as native-like interactions can play key roles in stabilising partially folded intermediate states.
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Sheena Radford has built on these findings to define key steps in the aberrant self-assembly of misfolded proteins into amyloid fibrils, particularly in dialysis related amyloidosis, and to relate these molecular processes to pathogenesis.
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Sheena Radford was elected a Fellow of the Academy of Medical Sciences in 2010.
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Sheena Radford is Professor of Structural Molecular Biology at the University of Leeds.
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Sheena Radford's achievements have involved the innovative application of biophysical techniques to protein folding problems.
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Sheena Radford has extended her research to encompass misfolding and disease and has developed new physical methods to study ultrafast processes.
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Sheena Radford's work on dialysis-dependent amyloidosis has shown that protein unfolding of beta-2-microglobulin is a key step in fibril formation.
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Sheena Radford was appointed Officer of the Order of the British Empire in the 2020 Birthday Honours for services to molecular biology research.