Stanozolol has mostly been discontinued, and remains available in only a few countries.
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Stanozolol has mostly been discontinued, and remains available in only a few countries.
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Stanozolol is one of the AAS commonly used as performance-enhancing drugs and is banned from use in sports competition under the auspices of the International Association of Athletics Federations and many other sporting bodies.
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Stanozolol has been used with some success to treat venous insufficiency.
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Stanozolol is used for physique- and performance-enhancing purposes by competitive athletes, bodybuilders, and powerlifters.
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Stanozolol is not a substrate for 5a-reductase as it is already 5a-reduced, and so is not potentiated in so-called "androgenic" tissues like the skin, hair follicles, and prostate gland.
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Stanozolol has high oral bioavailability, due to the presence of its C17a alkyl group and the resistance to gastrointestinal and liver metabolism that it results in.
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Stanozolol is metabolized in the liver, ultimately becoming glucuronide and sulfate conjugates.
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Stanozolol, known as 17a-methyl-2'H-androst-2-eno[3,2-c]pyrazol-17ß-ol, is a synthetic 17a-alkylated androstane steroid and a derivative of 5a-dihydrotestosterone with a methyl group at the C17a position and a pyrazole ring attached to the A ring of the steroid nucleus.
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Stanozolol is subject to extensive hepatic biotransformation by a variety of enzymatic pathways.
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Stanozolol is still used long-term to reduce the frequency of severity of attacks.
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Stanozolol is especially widely used by the athletes from post-Soviet countries.
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Stanozolol has been investigated in the treatment of a number of dermatological conditions including urticaria, hereditary angioedema, Raynaud's phenomenon, cryofibrinogenemia, and lipodermatosclerosis.
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