12 Facts About Testosterone

Testosterone is a steroid from the androstane class containing a ketone and a hydroxyl group at positions three and seventeen respectively.

Testosterone can be described as having virilising and anabolic effects .

Testosterone levels do not rely on physical presence of a partner; testosterone levels of men engaging in same-city and long-distance relationships are similar.

Testosterone deficiency is associated with an increased risk of metabolic syndrome, cardiovascular disease and mortality, which are sequelae of chronic inflammation.

Testosterone is used as a medication for the treatment of male hypogonadism, gender dysphoria, and certain types of breast cancer.

Testosterone is included in the World Health Organization's list of essential medicines, which are the most important medications needed in a basic health system.

Testosterone, via its active metabolite 3a-androstanediol, is a potent positive allosteric modulator of the GABAA receptor.

Testosterone has been found to act as an antagonist of the TrkA and p75, receptors for the neurotrophin nerve growth factor, with high affinity .

Testosterone is an antagonist of the sigma-1 receptor .

Testosterone is synthesized in far smaller total quantities in women by the adrenal glands, thecal cells of the ovaries, and, during pregnancy, by the placenta.

Testosterone reported in The Lancet that his vigor and feeling of well-being were markedly restored but the effects were transient, and Brown-Sequard's hopes for the compound were dashed.

Testosterone was identified as 17ß-hydroxyandrost-4-en-3-one, a solid polycyclic alcohol with a hydroxyl group at the 17th carbon atom.