12 Facts About Testosterone


Testosterone is a steroid from the androstane class containing a ketone and a hydroxyl group at positions three and seventeen respectively.

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Testosterone can be described as having virilising and anabolic effects .

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Testosterone levels do not rely on physical presence of a partner; testosterone levels of men engaging in same-city and long-distance relationships are similar.

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Testosterone deficiency is associated with an increased risk of metabolic syndrome, cardiovascular disease and mortality, which are sequelae of chronic inflammation.

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Testosterone is used as a medication for the treatment of male hypogonadism, gender dysphoria, and certain types of breast cancer.

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Testosterone is included in the World Health Organization's list of essential medicines, which are the most important medications needed in a basic health system.

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Testosterone, via its active metabolite 3a-androstanediol, is a potent positive allosteric modulator of the GABAA receptor.

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Testosterone has been found to act as an antagonist of the TrkA and p75, receptors for the neurotrophin nerve growth factor, with high affinity .

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Testosterone is an antagonist of the sigma-1 receptor .

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Testosterone is synthesized in far smaller total quantities in women by the adrenal glands, thecal cells of the ovaries, and, during pregnancy, by the placenta.

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Testosterone reported in The Lancet that his vigor and feeling of well-being were markedly restored but the effects were transient, and Brown-Sequard's hopes for the compound were dashed.

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Testosterone was identified as 17ß-hydroxyandrost-4-en-3-one, a solid polycyclic alcohol with a hydroxyl group at the 17th carbon atom.

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