1. Toine Manders represented the People's Party for Freedom and Democracy as part of the Alliance of Liberals and Democrats for Europe until 17 October 2013, when he changed party affiliations to lead 50PLUS in the 2014 European Parliament election, in which he failed to win reelection.
Toine Manders attended the Academy for Industrial Design in Tilburg, graduating in 1982.
Toine Manders proceeded to study law Maastricht University, earning his degree in 1993.
Toine Manders started his political career in the municipal council of Asten, of which he was a member between 1994 and 1999.
Toine Manders concurrently served as a member of the States-Provincial of North Brabant since 1995.
Toine Manders served for the People's Party for Freedom and Democracy in the European Parliament from 20 July 1999 until 17 October 2013 as part of the Alliance of Liberals and Democrats for Europe.
Toine Manders got enough preferences votes during each of the three elections to be chosen independent of his list position.
Toine Manders left the People's Party for Freedom and Democracy to become the party leader for the 50PLUS party in the 2014 European Parliament election, but the party didn't get enough votes for a seat.
Toine Manders felt that his former party had switched too much toward the political right, he agreed that the People's Party for Freedom and Democracy's decision to limit their MEP terms to three might have influenced his decision.
On 2 June 2020, Toine Manders left 50PLUS and joined the Christian Democratic Appeal party.
Toine Manders did not run for re-election in June 2024, and his term ended on 15 July 2024.
Since joining the European Parliament in 1999, Toine Manders served on the Committee on the Internal Market and Consumer Protection.
Toine Manders worked on legislation mandating that bank account numbers be checked against provided names in online transactions to prevent mistaken transactions.
In 2009, Toine Manders rejected as "outrageous" an allegation by a Protestant group that the flag of Europe is a marian symbol, saying that similar symbols were found in ancient Greece.