1. Vincenzo Cerundolo was an Italian medical researcher who was the Director of the Medical Research Council Human Immunology Unit at the University of Oxford, at the John Radcliffe Hospital and a Professor of Immunology at the University of Oxford.
Vincenzo Cerundolo was a Supernumerary Fellow at Merton College, Oxford.
Vincenzo Cerundolo was known for his discoveries in processing and presentation of cancer and viral peptides to T cells and lipids to invariant NKT cells.
Vincenzo Cerundolo was born in Lecce on 20 December 1959 to Vittorio Cerundolo and Colomba Vissicchio.
Vincenzo Cerundolo went to school at Liceo Scientifico De Giorgi and then to the University of Padua to study Medicine.
Vincenzo Cerundolo went on to complete a higher degree at the University of Padua at the Institute of Oncology supervised by Dino Collavo and Paola Zanovello.
Vincenzo Cerundolo was first to demonstrate that TAP genes located within the major histocompatibility complex transport peptides presented by MHC class I molecules and describe a novel clinical syndrome in patients with defective TAP genes.
Vincenzo Cerundolo characterised the relationship between the length of peptides and their binding affinity to MHC class I molecules, explaining the homogeneous length of peptides isolated from MHC class I molecules.
Vincenzo Cerundolo characterised the structural and kinetic mechanisms by which lipids bind to CD1 molecules and are recognized by T cells and demonstrated that harnessing CD1 restricted Natural killer T cell cells enhances antigen specific antibody and T cell responses.
Vincenzo Cerundolo became Director of the MRC Human Immunology Unit in 2010.