Wilson's disease is a genetic disorder in which excess copper builds up in the body.
| FactSnippet No. 2,499,322 |
10 Facts About Wilson's disease
2.
Wilson's disease is caused by a mutation in the Wilson disease protein gene.
| FactSnippet No. 2,499,323 |
3.
Wilson's disease is typically treated with dietary changes and medication.
| FactSnippet No. 2,499,324 |
4.
Complications of Wilson's disease can include liver failure, liver cancer and kidney problems.
| FactSnippet No. 2,499,325 |
5.
Normal variation in the PRNP gene can modify the course of the Wilson's disease by delaying the age of onset and affecting the type of symptoms that develop.
| FactSnippet No. 2,499,326 |
6.
Wilson's disease is the most common from a group of hereditary diseases that cause copper overload in the liver.
| FactSnippet No. 2,499,327 |
7.
Urine copper is elevated in Wilson's disease and is collected for 24 hours in a bottle with a copper-free liner.
| FactSnippet No. 2,499,328 |
8.
High urine copper levels are not unique to Wilson's disease; they are sometimes observed in autoimmune hepatitis and in cholestasis.
| FactSnippet No. 2,499,329 |
9.
Regional distributions of genes associated with Wilson's disease are important to follow, as this can help clinicians design appropriate screening strategies.
| FactSnippet No. 2,499,330 |
10.
Liver transplantation is an effective cure for Wilson's disease but is used only in particular scenarios because of the risks and complications associated with the procedure.
| FactSnippet No. 2,499,331 |