16 Facts About Alprazolam


Alprazolam, sold under the brand name Xanax, among others, is a fast-acting, potent tranquilizer of medium duration in the triazolobenzodiazepine class, which are benzodiazepines fused with a triazole ring.

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Alprazolam was patented in 1971 and approved for medical use in the United States in 1981.

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Alprazolam is a Schedule IV controlled substance and is a common drug of abuse.

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Alprazolam is mostly used in short-term management of anxiety disorders, panic disorders, and nausea due to chemotherapy.

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Alprazolam is indicated for the treatment of generalized anxiety disorder and panic disorder with or without agoraphobia in adults.

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Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks.

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Alprazolam is not recommended in Australia for the treatment of panic disorder because of concerns regarding tolerance, dependence, and abuse.

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Alprazolam is recommended by the World Federation of Societies of Biological Psychiatry for treatment-resistant cases of panic disorder where there is no history of tolerance or dependence.

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Alprazolam is a positive allosteric modulator of the gamma-aminobutyric acid type A receptor.

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Alprazolam is classed as a high-potency triazolobenzodiazepine: a benzodiazepine with a triazole ring attached to its structure.

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Alprazolam is metabolized in the liver, mostly by the enzyme cytochrome P450 3A4 .

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Alprazolam is a triazole and benzodiazepine derivative substituted with a phenyl group at position 6, with a chlorine atom at position 8 and with a methyl group at position 1.

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Alprazolam is covered under, which was filed on 29 October 1969, granted on 19 October 1976, and expired in September 1993.

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Alprazolam is one of the most commonly prescribed and misused benzodiazepines in the United States.

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Alprazolam is not very soluble in water—when crushed in water it does not fully dissolve .

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Alprazolam is available in English-speaking countries under the following brand names:.

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