11 Facts About Bacterial spores

Thermo-resistant endoBacterial spores were first hypothesized by Ferdinand Cohn after studying Bacillus subtilis growth on cheese after boiling the cheese.

Bacterial spores's notion of spores being the reproductive mechanism for the growth was a large blow to the previous suggestions of spontaneous generation.

EndoBacterial spores retain viability indefinitely and they can germinate into vegetative cells under the appropriate conditions.

EndoBacterial spores have survived thousands of years until environmental stimuli trigger germination.

Terminal endoBacterial spores are seen at the poles of cells, whereas central endoBacterial spores are more or less in the middle.

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Subterminal endoBacterial spores are those between these two extremes, usually seen far enough towards the poles but close enough to the center so as not to be considered either terminal or central.

Examples of bacteria having terminal endoBacterial spores include Clostridium tetani, the pathogen that causes the disease tetanus.

EndoBacterial spores are resistant to most agents that would normally kill the vegetative cells they formed from.

Unlike persister cells, endoBacterial spores are the result of a morphological differentiation process triggered by nutrient limitation in the environment; endosporulation is initiated by quorum sensing within the "starving" population.

In contrast, "high level disinfection" does not kill endoBacterial spores but is used for instruments such as a colonoscope that do not enter sterile bodily cavities.

Bacillus subtilis Bacterial spores are useful for the expression of recombinant proteins and in particular for the surface display of peptides and proteins as a tool for fundamental and applied research in the fields of microbiology, biotechnology and vaccination.