10 Facts About Brucine

1.

Brucine, is an alkaloid closely related to strychnine, most commonly found in the Strychnos nux-vomica tree.

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2.

Brucine poisoning is rare, since it is usually ingested with strychnine, and strychnine is more toxic than brucine.

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3.

Brucine is named from the genus Brucea, named after James Bruce who brought back Brucea antidysenterica from Ethiopia.

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4.

Brucine was discovered in 1819 by Pelletier and Caventou in the bark of the Strychnos nux-vomica tree.

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5.

Brucine can be detected and quantified using liquid chromatography-mass spectrometry.

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6.

Brucine has been used in fractional distillation in acetone in order to resolve dihydroxy fatty acids, as well as diarylcarbinols.

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7.

Brucine is used in traditional Chinese medicine as an anti-inflammatory and analgesic agent, as well as in some Ayurveda and homeopathy drugs.

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8.

Brucine is one of the many chemicals used as a denaturant to make alcohol unfit for human consumption.

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9.

Brucine in mentioned in the 1972 version of The Mechanic, in which the hitman Steve McKenna betrays his mentor, aging hitman Arthur Bishop, using a celebratory glass of wine spiked with brucine, leaving Bishop to die of an apparent heart attack.

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10.

Brucine intoxication occurs very rarely, since it is usually ingested with strychnine.

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