11 Facts About Fenfluramine

1.

Fenfluramine, sold under the brand name Fintepla, is a serotonergic medication used for the treatment of seizures associated with Dravet syndrome and Lennox–Gastaut syndrome.

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2.

Fenfluramine was used for weight loss both alone under the brand name Pondimin and in combination with phentermine under the brand name Fen-Phen among others.

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3.

Fenfluramine was developed in the early 1960s and was first introduced for medical use as an appetite suppressant in France in 1963 followed by approval in the United States in 1973.

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4.

Fenfluramine is a schedule IV controlled substance in the United States.

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5.

Fenfluramine is indicated for the treatment of seizures associated with Dravet syndrome and Lennox–Gastaut syndrome in people age two and older.

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6.

Fenfluramine was formerly used as an appetite suppressant in the treatment of obesity, but was withdrawn for this use due to cardiovascular toxicity.

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7.

Fenfluramine is a substituted amphetamine and is known as 3-trifluoromethyl-N-ethylamphetamine.

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8.

Fenfluramine was developed in the early 1960s and was introduced in France in 1963.

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9.

Fenfluramine was withdrawn from the U S market in 1997 after reports of heart valve disease and continued findings of pulmonary hypertension, including a condition known as cardiac fibrosis.

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10.

Fenfluramine was an appetite suppressant which was used to treat obesity.

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11.

Fenfluramine was approved for medical use in the European Union in December 2020.

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