Fluvoxamine, sold under the brand name Luvox among others, is an antidepressant of the selective serotonin reuptake inhibitor class.
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10 Facts About Fluvoxamine
2.
Fluvoxamine is approved in the United States for OCD, and social anxiety disorder.
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3.
Fluvoxamine is effective for GAD, social anxiety disorder, panic disorder and separation anxiety disorder in children and adolescents.
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4.
Fluvoxamine has been observed to increase serum concentrations of mirtazapine, which is mainly metabolized by CYP1A2, CYP2D6, and CYP3A4, by three- to four-fold in humans.
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5.
Fluvoxamine seriously affects the pharmacokinetics of tizanidine and increases the intensity and duration of its effects.
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6.
Fluvoxamine is a potent selective serotonin reuptake inhibitor with around 100-fold affinity for the serotonin transporter over the norepinephrine transporter.
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7.
Fluvoxamine was developed by Kali-Duphar, part of Solvay Pharmaceuticals, Belgium, now Abbott Laboratories, and introduced as Floxyfral in Switzerland in 1983.
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8.
Fluvoxamine was the first SSRI to be registered for the treatment of obsessive compulsive disorder in children by the FDA in 1997.
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9.
Fluvoxamine was the first SSRI approved for clinical use in the United Kingdom.
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10.
Fluvoxamine is a common finding in waters near human settlement.
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