1. Jennifer Lippincott-Schwartz is a Senior Group Leader at Howard Hughes Medical Institute's Janelia Research Campus and a founding member of the Neuronal Cell Biology Program at Janelia.
15 Facts About Jennifer Lippincott-Schwartz
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Jennifer Lippincott-Schwartz's research revealed that the organelles of eukaryotic cells are dynamic, self-organized structures that constantly regenerate themselves through intracellular vesicle traffic, rather than static structures.
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Jennifer Lippincott-Schwartz is a pioneer in developing live cell imaging techniques to study the dynamic interactions of molecules in cells, including photobleaching and photoactivation techniques which allow investigation of subcellular localization, mobility, transport routes, and turnover of important cellular proteins related to membrane trafficking and compartmentalization.
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Additionally, Jennifer Lippincott-Schwartz's laboratory demonstrated that Golgi enzymes constitutively recycle back to the endoplasmic reticulum and that such recycling plays a central role in the maintenance, biogenesis, and inheritance of the Golgi apparatus in mammalian cells.
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Jennifer Lippincott-Schwartz has dedicated her most recent lab research to photoactivation localization microscopy, which allows the viewing of molecular distributions of high densities at the nano-scale.
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Jennifer Lippincott-Schwartz was born on October 19,1952, in Manhattan, Kansas.
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Jennifer Lippincott-Schwartz's father was a professor of physical chemistry at the University of Maryland and a periodic table could be found hanging in her family's household kitchen.
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Jennifer Lippincott-Schwartz attended Swarthmore College, where she majored in psychology and philosophy and graduated with honors from Swarthmore College in 1974.
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Jennifer Lippincott-Schwartz taught science at a girl's high school in Kenya for two years before returning to the USA and entering a Master's program in Biology at Stanford University where she worked on DNA repair in the laboratory of Philip Hanawalt.
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Jennifer Lippincott-Schwartz became a staff fellow at the National Institute of Child Health and Human Development at NIH in 1990.
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Jennifer Lippincott-Schwartz refined the technique of fluorescence recovery after photobleaching to use in studying the dynamics of membrane proteins.
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Jennifer Lippincott-Schwartz subsequently introduced photoactivatable GFP that increases its fluorescence after irradiation.
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Jennifer Lippincott-Schwartz has used PALM to assess the stoichiometry and composition of membrane receptors and has collaborated with Vladislav Verkhusha of Albert Einstein College of Medicine in New York to develop two-color PALM.
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Jennifer Lippincott-Schwartz used a combination of five super-resolution techniques to show that the endoplasmic reticulum is composed of a dense tubular matrix, instead of the sheets seen at lower resolution.
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In 2016, Jennifer Lippincott-Schwartz moved from NIH to the Janelia Research Campus of the Howard Hughes Medical Institute to initiate the Neuronal Cell Biology Program at Janelia.