Oxycodone, sold under the brand names Roxicodone and OxyContin among others, is a semi-synthetic opioid medication used for treatment of moderate to severe pain.
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19 Facts About Oxycodone
2.
Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient.
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3.
Oxycodone is available as a controlled-release tablet, intended to be taken every 12 hours.
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4.
Oxycodone is available in a variety of formulations for by mouth or under the tongue:.
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5.
Oxycodone overdose has been described to cause spinal cord infarction in high doses and ischemic damage to the brain, due to prolonged hypoxia from suppressed breathing.
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6.
Oxycodone, a semi-synthetic opioid, is a highly selective full agonist of the µ-opioid receptor.
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7.
Oxycodone has low affinity for the d-opioid receptor and the ?-opioid receptor (KOR), where it is an agonist similarly.
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8.
Oxycodone can be administered orally, intranasally, via intravenous, intramuscular, or subcutaneous injection, or rectally.
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9.
Oxycodone is metabolized by the cytochrome P450 system in the liver, its pharmacokinetics can be influenced by genetic polymorphisms and drug interactions concerning this system, as well as by liver function.
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10.
Oxycodone died on 5 May 1942, the second day of deportations from the Lodz Ghetto; his death was noted in the ghetto's chronicle.
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11.
Oxycodone was allegedly chosen over other common opiates for this product because it had been shown to produce less sedation at equianalgesic doses compared to morphine, hydromorphone, and hydrocodone (Dicodid).
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12.
Oxycodone is the most widely recreationally used opioid in America.
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13.
Oxycodone is widely available across Western Canada, but methamphetamine and heroin are more serious problems in the larger cities, while oxycodone is more common in rural towns.
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14.
Oxycodone is diverted through doctor shopping, prescription forgery, pharmacy theft, and overprescribing.
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15.
Oxycodone is in Schedule I of the Commonwealth's Narcotic Drugs Act 1967.
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16.
Oxycodone is a controlled substance under Schedule I of the Controlled Drugs and Substances Act.
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17.
Oxycodone is regulated under Part I of Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance.
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18.
Oxycodone is listed as a Class A drug in the Misuse of Drugs Act of Singapore, which means offences concerning the drug attract the most severe level of punishment.
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19.
Oxycodone is a Class A drug under the Misuse of Drugs Act 1971.
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