Powassan virus is a Flavivirus transmitted by ticks, found in North America and in the Russian Far East.
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10 Facts About Powassan virus
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The Powassan virus exists in North America and causes long-term neurological sequelae.
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Powassan virus is found in the warm climate across Eurasia, where it is part of the tick-borne encephalitis virus-complex.
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Powassan virus is an RNA virus split into two separate lineages: Lineage I, labeled as the “prototype” lineage; and Lineage II, the deer tick virus lineage.
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Powassan virus infection is rarely diagnosed as a cause of encephalitis; however, when it is, Powassan encephalitis is severe, and neurologic sequelae are common.
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Powassan virus encephalitis has symptoms compatible with acute disseminated encephalomyelitis, oftentimes making it difficult to diagnose.
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Powassan virus encephalitis is a challenge to diagnose because there are only a few laboratories that offer testing, the most effective being serologic testing.
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Powassan virus survived with normal motor and verbal development on follow-up at the age of 10 months, but a head MRI showed severely abnormal brain conditions, including scarring and softening in the thalamus and basal ganglia on both sides, and volume loss and early mineralization in the left basal ganglia.
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10.
POWV has different genetic variations including deer tick Powassan virus which is transmitted by the black legged deer tick, Ixodes scapularis.
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