Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid.
| FactSnippet No. 870,827 |
10 Facts About Rabeprazole
2.
Rabeprazole was patented in 1986, and approved for medical use in 1997.
| FactSnippet No. 870,828 |
3.
Rabeprazole is useful alongside antibiotic therapy for the treatment of the pathogen Helicobacter pylori, which otherwise thrives in acidic environments.
| FactSnippet No. 870,829 |
4.
Rabeprazole-based products, like other proton pump inhibitor products, have to be formulated in delayed-release tablets to protect the active medication from being degraded by the acid of the stomach before being absorbed.
| FactSnippet No. 870,830 |
5.
Rabeprazole is associated with elevated serum gastrin levels, which are thought to be dependent upon the degree of CYP2C19 metabolism the drug undergoes.
| FactSnippet No. 870,831 |
6.
Rabeprazole is classified as a substituted benzimidazole, like omeprazole, lansoprazole, and pantoprazole.
| FactSnippet No. 870,832 |
7.
Rabeprazole possess properties of both acids and bases, making it an amphotere.
| FactSnippet No. 870,833 |
8.
Rabeprazole is characterized as a white to yellowish-white solid in its pure form.
| FactSnippet No. 870,834 |
9.
Rabeprazole is very soluble in water and methanol, freely soluble in ethanol, chloroform, and ethyl acetate, and is insoluble in ether and n-hexane.
| FactSnippet No. 870,835 |
10.
Rabeprazole is approved in the United States and the United Kingdom for prescription use only.
| FactSnippet No. 870,836 |