15 Facts About Rectal cancer

The individual likelihood of survival depends on how advanced the Rectal cancer is, whether or not all the Rectal cancer can be removed with surgery and the person's overall health.

Signs and symptoms of colorectal cancer depend on the location of the tumor in the bowel, and whether it has spread elsewhere in the body .

Colorectal cancer is a disease originating from the epithelial cells lining the colon or rectum of the gastrointestinal tract, most frequently as a result of mutations in the Wnt signaling pathway that increase signaling activity.

The polyp to cancer sequence describes the phases of transition from benign tumours into colorectal cancer over many years.

Novel Epigenome-based Classification of colorectal cancer was proposed in 2021 introducing 4 enhancer subtypes in people with CRC.

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Colorectal cancer diagnosis is performed by sampling of areas of the colon suspicious for possible tumor development, typically during colonoscopy or sigmoidoscopy, depending on the location of the lesion.

The risk of colon Rectal cancer can be reduced by maintaining a normal body weight through a combination of sufficient exercise and eating a healthy diet.

For people with localized Rectal cancer, the preferred treatment is complete surgical removal with adequate margins, with the attempt of achieving a cure.

The role of chemotherapy in Stage II colon Rectal cancer is debatable, and is usually not offered unless risk factors such as T4 tumor, undifferentiated tumor, vascular and perineural invasion or inadequate lymph node sampling is identified.

For stage III and Stage IV colon Rectal cancer, chemotherapy is an integral part of treatment.

The use of radiotherapy in colon Rectal cancer is not routine due to the sensitivity of the bowels to radiation.

In people with incurable colorectal cancer, palliative care can consist of procedures that relieve symptoms or complications from the cancer but do not attempt to cure the underlying cancer, thereby improving quality of life.

In clinical studies, a pro-inflammatory response was found in people with stage II-III colorectal cancer who underwent 2 weeks of moderate exercise after completing their primary therapy.

Improvements in aerobic fitness, Rectal cancer-related fatigue and health-related quality of life have been reported in the short term.

Rectal cancer has been diagnosed in an Ancient Egyptian mummy who had lived in the Dakhleh Oasis during the Ptolemaic period.