14 Facts About Ribosomes

1.

Ribosomes, called Palade granules, are macromolecular machines, found within all cells, that perform biological protein synthesis .

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2.

Ribosomes consist of two major components: the small and large ribosomal subunits.

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3.

Ribosomes bind to messenger RNAs and use their sequences for determining the correct sequence of amino acids to generate a given protein.

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4.

Ribosomes are ribozymes, because the catalytic peptidyl transferase activity that links amino acids together is performed by the ribosomal RNA.

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5.

Ribosomes are often associated with the intracellular membranes that make up the rough endoplasmic reticulum.

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6.

Ribosomes were first observed in the mid-1950s by Romanian-American cell biologist George Emil Palade, using an electron microscope, as dense particles or granules.

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7.

Ribosomes consist of two subunits that fit together and work as one to translate the mRNA into a polypeptide chain during protein synthesis .

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8.

Ribosomes in chloroplasts are different: Antibiotic resistance in chloroplast ribosomal proteins is a trait that has to be introduced as a marker, with genetic engineering.

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9.

Ribosomes are minute particles consisting of RNA and associated proteins that function to synthesize proteins.

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10.

Ribosomes can be found floating within the cytoplasm or attached to the endoplasmic reticulum.

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11.

Ribosomes act as catalysts in two extremely important biological processes called peptidyl transfer and peptidyl hydrolysis The "PT center is responsible for producing protein bonds during protein elongation".

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12.

Ribosomes are the workplaces of protein biosynthesis, the process of translating mRNA into protein.

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13.

Ribosomes are sometimes referred to as organelles, but the use of the term organelle is often restricted to describing sub-cellular components that include a phospholipid membrane, which ribosomes, being entirely particulate, do not.

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14.

Ribosomes are compositionally heterogeneous between species and even within the same cell, as evidenced by the existence of cytoplasmic and mitochondria ribosomes within the same eukaryotic cells.

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